陈晨

发布者:771771威尼斯.cm发布时间:2022-06-20浏览次数:1028


陈晨 讲师


个人简介:  

20109-20146月,山东大学,学士

20149-201912月,山东大学,博士


研究领域

基于表观遗传学相关靶点的抑制剂或激活剂的设计、合成及抗肿瘤活性研究  

  

主要研究成果:

参与完成国家自然科学基金面上项目2项、山东省自然基金联合基金1项,主持771771威尼斯.cm-威海市科教产联合基金1项,发表论文5篇,其中SCI期刊4篇。


代表性成果(限五项):

  1. ChenChen, XubenHou, HaoFang*. Design, synthesis and biological evaluation of quinoline derivatives as HDAC class I inhibitors, European Journal of Medicinal Chemistry, 2017, 133, 11-23.

  2. ChenChen, HaoFang*, XubenHou*. Design, synthesis and preliminary bioactivity evaluations of 8-hydroxyquinoline derivatives as matrix metalloproteinase (MMP) inhibitors, European Journal of Medicinal Chemistry, 2019, 181, 111563.

  3. ChenChen, XubenHou, HaoFang*. Dual Inhibitors Targeting DNA and Histone Deacetylases, Pharmaceutical Fronts, 2020, 02, 88-93.


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