徐琦 讲师
个人简介:
2010年9月-2014年6月,山东大学(威海),学士
2014年9月-2019年6月,中国科学院海洋研究所,博士
2019年7月-至今,771771威尼斯.cm 771771威尼斯.cm
研究领域:
基于“营养-肠道菌群-生理机能”轴理论的改性膳食纤维对高发代谢性疾病的防治作用研究
主要研究成果:
参与完成国家自然科学基金面上项目、青年基金,山东省重点研发计划和中国科学院前沿科学重点研究项目等6项,以第一作者发表论文5篇,其中SCI期刊5篇,SCI引用45次。申请专利1项。
代表性成果(限五项):
1. Zhongjun Fan #; Qi Xu#; Changhui Wang; Xiukun Lin; Quanbin Wang; Ning Wu*;A tropomyosin-like Meretrix meretrix Linnaeus polypeptide inhibits theproliferation and metastasis of glioma cells via microtubule polymerization and FAK/Akt/MMPs signaling, International Journal of Biological Macromolecules,2020, 145: 154-164.
2. Qi Xu#; Ning Wu#; Xiangqian Li; Chuanlong Guo; Chao Li; Bo Jiang; Huaizhi Wang; Dayong Shi*;Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway, Cell Death & Disease, 2019, 10(12): 874.
3. Qi Xu#; Jiao Luo; Ning Wu; Renshuai Zhang; Dayong Shi*; BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes, International Journal of Biological Macromolecules,2018, 106: 379-386.
4. Qi Xu#; Lijun Wang; Jiao Luo; Dayong Shi*; The Hot and Potential Targets of Type 2 Diabetes Mellitus Treatment in Recent Decade, Current Drug Targets, 2018, 19(1): 55-695.
5. Xiangqian Li#; Qi Xu#; Jiao Luo; Lijun Wang; Bo Jiang; Renshuai Zhang; Dayong Shi*; Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B, European Journal of Medicinal Chemistry, 2017, 136: 348-359.